Furocef 250mg Tablet

✔️ Uses of Furocef 250mg Tablet

• Bacterial Infections

✔️ How does Furocef 250mg Tablet work?

Furocef 250mg Tablet works by preventing the formation of the bacterial cell wall. This helps in stopping the growth and multiplication of the bacteria, eventually killing them.

✔️ Side Effects of Furocef 250mg Tablet

• Headache
• Dizziness
• Stomach upset
• Overgrowth of candida (fungal skin infection)
• Unpleasant taste in the mouth
• Diaper rashes
• Eosinophilia (increased disease-fighting cells/WBC)

✔️ Quick Suggestions:

• Furocef 250mg Tablet is used to treat airway, lung, throat, skin, urinary tract, and gynecological infections.
• Take this tablet as directed by your doctor. Do not take more than the prescribed dose.
• Furocef 250mg Tablet should be taken with food, to reduce stomach upset.
• Complete the full course of treatment, even if you start feeling better. This will help prevent the infection from coming back.
• Do not stop taking the medication without consulting your doctor, as this could lead to the development of antibiotic resistance.
• Before taking this medicine, inform your doctor about all your medications and medical history.
• Nausea, diarrhea, stomach pain, and dizziness can be seen as side effects of this medicine, if side effects bother you please inform your doctor.
• Inform your doctor if you are pregnant or breastfeeding before taking Furocef 250mg Tablet.
• Inform your doctor if you have a history of allergy to cephalosporin antibiotics.

✔️ Indication of Furocef 250mg Tablet

Furocef 250mg Tablet is indeed a versatile antibiotic used to treat various bacterial infections, as described below:

1. Pharyngitis/Tonsillitis/Pharyngotonsillitis: Infections causing throat and tonsil swelling and soreness.
2. Sinusitis: Infections causing inflammation of the membranes lining the nose and surrounding sinuses.
3. Bronchitis: Infections leading to swelling and irritation of bronchial tubes in the lungs.
4. Skin and Soft Tissue Infections: Infections affecting the skin and its supporting structures.
5. Urinary Tract Infections: Infections in the urinary system, including the kidneys, bladder, ureters, or urethra.
6. Lyme Disease: An infection caused by Borrelia burgdorferi transmitted through tick bites.
7. Gonorrhoea: A sexually transmitted infection caused by Neisseria gonorrhea bacteria.

Furocef 250mg Tablet is effective in treating these bacterial infections, and it should be used as prescribed by the healthcare provider to ensure proper treatment and prevent antibiotic resistance.

✔️ Pharmacology

Cefuroxime, as a cephalosporin antibiotic, works by binding to the penicillin-binding proteins (PBPs) present in the bacterial cell wall. These PBPs are essential for the synthesis of peptidoglycan, a crucial component of the bacterial cell wall. By inhibiting the final transpeptidation step of peptidoglycan synthesis, cefuroxime disrupts the formation of a stable cell wall structure. This inhibition leads to the weakening of the bacterial cell wall, making it unable to withstand the internal osmotic pressure, ultimately causing bacterial cell death. This mechanism of action is vital in treating bacterial infections caused by susceptible organisms.

✔️ Dosage & Administration of Furocef 250mg Tablet

Dosage of Furocef 250mg Tablet:

Adolescents and adults (13 years and older):

• Pharyngitis/tonsillitis: 250 mg twice daily for 5-10 days
• Acute bacterial maxillary sinusitis: 250 mg twice daily for 10 days
• Acute bacterial exacerbation of chronic bronchitis: 250-500 mg twice daily for 10 days
• Secondary bacterial infections of acute bronchitis: 250-500 mg twice daily for 5-10 days
• Uncomplicated skin and skin structure infections: 250-500 mg twice daily for 10 days
• Uncomplicated urinary tract infections: 250 mg twice daily for 7-10 days
• Uncomplicated Gonorrhea: 1000 mg single dose
• Community-acquired pneumonia: 250-500 mg twice daily for 5-10 days
• MDR Typhoid Fever: 500 mg twice daily for 10-14 days
• Early Lyme disease: 500 mg twice daily for 20 days

Pediatric Patients (3 months to 12 years):

• Pharyngitis/Tonsillitis: 20 mg/kg/day twice daily for 5-10 days
• Acute otitis media: 30 mg/kg/day twice daily for 10 days
• Acute bacterial maxillary sinusitis: 30 mg/kg/day twice daily for 10 days
• Impetigo: 30 mg/kg/day twice daily for 10 days

Please take Furocef 250mg Tablet as advised by your physician. Your doctor will decide the correct dose and duration based on your age, body weight, and severity of infection.

✔️ Interaction

Furocef 250mg Tablet may interact with various drugs and should be avoided with oral birth control pills, medicines that reduce gastric acidity (like antacids, omeprazole), immuno-suppressing drugs (mycophenolate or mycophenolic acid), medicines used for reducing uric acid (probenecid), and certain urine glucose tests. It also interacts with typhoid and BCG vaccines.

Avoid consuming grapefruit juice and dietary supplements containing minerals like calcium, as they may interfere with the effectiveness of the antibiotic.

Furocef 250mg Tablet should not be used in the presence of colitis, kidney disease, patients planning for ferricyanide tests, patients on dialysis, liver disease, epilepsy (fits), and diarrhea. It is important to consult with your doctor if you have any of these conditions before taking the medication.

✔️ Contraindications

• If you are allergic to cefuroxime or other ingredients of the Furocef 250mg Tablet.
• If you have experienced an allergic reaction upon the use of certain antibiotics from the class of Penicillins, Monobactams, Carbapenems, or other Beta-Lactam antibiotics.

✔️ Pregnancy & Lactation

Cefuroxime is classified as a pregnancy category B by the US Food and Drug Administration. However, no appropriate and well-controlled trials in pregnant women have been conducted. Because animal reproduction studies do not always anticipate a human response, this medication should only be taken during pregnancy if absolutely necessary. Human milk has been found to contain cefuroxime. When Cefuroxime is given to a nursing mother, care should be used.

✔️ Precautions & Warnings

• People taking Furocef 250mg Tablet who have allergic reactions to penicillin or other beta-lactam antibiotics should exercise special care. Combining Furocef 250mg Tablet with other antibiotics may lead to a fungal skin infection called Candida. Prolonged use of Furocef 250mg Tablet may cause an overgrowth of other pathogens like enterococci and Clostridium difficile, which can be prevented by stopping the medication.
• Cases of colitis (inflammatory bowel disease) have been reported with Furocef 250mg Tablet use, so proper diagnosis is essential for patients experiencing diarrhea after taking the medication. If diarrhea persists, abdominal cramps may occur, and in such cases, Furocef 250mg Tablet should be discontinued immediately.
• The Jarisch-Herxheimer reaction, caused by toxins released by bacteria upon their death during antibiotic treatment, has been observed in patients using Furocef 250mg Tablet for Lyme disease treatment.
• It's important to be cautious while taking Furocef 250mg Tablet as it may affect cognitive and motor functions, leading to dizziness. Patients should be warned to exercise caution when driving or operating machinery.

✔️ Storage Conditions

• Store the Furocef 250mg Tablet in a cool and dry place & protect it from sunlight.
• Keep it out of the reach of children and pets.
• Discard any unused medicine properly. Do not flush it in the toilet or throw it into the drain.